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Installing XAMPP on same Computer as plain MySQL installation

I've seen a lot of articles about running two instances of MySQL on the same computer through changing the config file and using a separate port among other things I'm sure I didn't read.

This is not what I'm asking, though. What I want to know is if there is anything I need to be concerned about when it comes to having the XAMPP installation and my existing MySQL installation on a single computer. Is there anything I need to know? My hardware is a bit dated and struggles running a VM with another Windows 10 running. I could try to stretch the hardware as much as possible but if there's nothing to worry about when having those two RDBMSs on the same machine but only one running at a time, I'd rather do that.